Substances within skinŠ—Ès uppermost layers that help keep it smooth, hydrated and healthy-looking. Topical application helps reinforce skinŠ—Ès surface so skin takes on a younger, replenished appearance.
NMFs make up an expansive group of ingredients that include amino acids, lactic acid, sodium PCA, various sugars and minerals, and peptides. Together with the naturally-occurring lipids in skin (examples would be ceramides, cholesterol, and glycosaminoglycans), NMFŠ—Ès work to keep skinŠ—Ès surface intact and supple.
It is worth noting that routine exposure to sensitizing ingredients like drying cleanisng agents and denatured alcohol cause serious depletion of skinŠ—Ès natural moisturizing factors, leading to visibly dry, tight-feeling, flaky skin.
References for this information:
Acta-dermato Venerologica, November 2016, pages 880-884
Journal of Cosmetic Science, January-February 2010, pages 13-22
Skin Pharmacology and Physiology, SeptemberŠ—–October 2004, pages 207Š—–213
Progressive Lipid Research, January 2003, pages 1Š—–36
Journal of Lipid Research, May 2002, pages 794Š—–804
Clinical Geriatric Medicine, February 2002, pages 103Š—–120
Journal of the European Academy of Dermatology and Venereology, November 2002, pages 587Š—–594
Journal of Investigative Dermatology, May 1996, pages 1096Š—–1101
British Journal of Dermatology, November 1995, pages 679Š—–685